[Lisa_seminaires] [mila-tous] [Tea Talk] Anne Churchland (Cold Spring Harbor Laboratory) June 29 2018 10:30 AA3195

xavier bouthillier xavier.bouthillier at gmail.com
Mer 27 Juin 10:37:43 EDT 2018


Due to current migration to mila.bluejeans, we will use previous streaming
link: https://bluejeans.com/809027115/webrtc

On Tue, Jun 26, 2018 at 2:07 PM, Michael Noukhovitch <mnoukhov at gmail.com>
wrote:

> This week we have *Anne Churchland * from * Cold Spring Harbor Laboratory
> * giving a talk on *June 29 2018* at *10:30* in room *AA3195*
>
> This talk may be streamed as usual here
> <https://mila.bluejeans.com/1365483656/webrtc>
> And you can sign up to meet the speaker here
> <https://calendar.google.com/calendar/selfsched?sstoken=UVBVTVF0X25Nd09LfGRlZmF1bHR8ZWQ5MmNlYWMxODI4OWVkNmUzNGU3OTE4ZDExMGI0YTk>
>
> Don't even think about it! Decide to come to the tea talk and let your
> feet spontaneously guide the way.
> Michael
>
> *TITLE* Spontaneous movements dominate cortical activity during
> sensory-guided decision making
>
> *KEYWORDS *neuroscience, decision-making, neuro-imaging
>
> *ABSTRACT*
> Animals continually produce a wide array of spontaneous and learned
> movements and undergo rapid internal state transitions. Most work in
> neuroscience ignores this “internal backdrop” and instead focuses on
> neural activity aligned to task-imposed variables such as sensory stimuli.
> We sought to understand the joint effects of internal backdrop vs.
> task-imposed variables. We measured neural activity using calcium imaging
> via a widefield macroscope during decision-making. Surprisingly, the impact
> of the internal backdrop dwarfed task-imposed sensory and
> cognitive signals. This dominance was comparable in novice and expert
> decision-makers and was even stronger in single neuron measurements from
> frontal cortex. These results highlight spontaneous and learned movements
> as the main determinant of large-scale cortical activity. By leveraging a
> wide array of animal movements, our model offers a very general method for
> separating the impact of internal backdrop from task-imposed
> neural activity.
>
> *BIO* Anne K. Churchland received her Ph.D. in neuroscience from the
> University of California, San Francisco, advised by Dr. Stephen Lisberger.
> She then did a postdoctoral fellowship with Dr. Michael Shadlen at the
> University of Washington in the Physiology and Biophysics Department. Her
> postdoctoral work focused on mechanisms of decision making in nonhuman
> primates and included both experimental and theoretical work. The latter
> was funded by a Pathways to Independence (K99) Award from the National Eye
> Institute. In 2010, she became an assistant professor at Cold Spring Harbor
> Laboratory. In starting her own laboratory, Professor Churchland began
> studying decision making using rodent models to take advantage of emerging
> tools for circuit dissection which are readily available in rodents. Since
> then, her laboratory has been a major player in bringing behavioral
> paradigms to rodents that have been successful in elucidating neural
> mechanisms in primates. These include perceptual decision making and
> multisensory integration. Most recently, she has teamed up with other 20
> other researchers to for the International Brain Laboratory, a
> collaboration between theorists and experimentalists aiming to understand
> the neural computations supporting decision-making. Since joining Cold
> Spring Harbor Laboratory, Professor Churchland has been the recipient of
> awards from the McKnight Foundation, the Pew Charitable Trusts, the
> Klingenstein-Simons Foundation, the Simons Collaboration on the Global
> Brain, the John Merck Fund and the Chapman Foundations. In addition to her
> scientific work, Professor Churchland runs science outreach activities at
> public schools and co-directed the Undergraduate Research Program at Cold
> Spring Harbor Laboratory. She also maintains a blog about neuroscience
> research that is directed at a mainstream audience; its recent focus is on
> reviewing papers on the preprint server. Professor Churchland also funded
> anneslist.net, a resource highlighting women in systems and computational
> neuroscience. She received the 2017 Louise Hanson Marshall Special
> Recognition Award from the Society for Neuroscience for promoting diversity
> in the field and the 2012 Janett Rosenberg Trubatch Career Development
> Award for creativity in research prior to tenure.
>
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