[Lisa_seminaires] [mila-tous] [Tea Talk] Anne Churchland (Cold Spring Harbor Laboratory) June 29 2018 10:30 AA3195

xavier bouthillier xavier.bouthillier at gmail.com
Mer 27 Juin 15:42:37 EDT 2018


Sorry for the confusion, migration is already over. The link in Michael's
email is the one we will use: https://mila.bluejeans.com/1365483656/webrtc

On Wed, Jun 27, 2018 at 10:37 AM, xavier bouthillier <
xavier.bouthillier at gmail.com> wrote:

> Due to current migration to mila.bluejeans, we will use previous streaming
> link: https://bluejeans.com/809027115/webrtc
>
> On Tue, Jun 26, 2018 at 2:07 PM, Michael Noukhovitch <mnoukhov at gmail.com>
> wrote:
>
>> This week we have *Anne Churchland * from * Cold Spring Harbor
>> Laboratory * giving a talk on *June 29 2018* at *10:30* in room *AA3195*
>>
>> This talk may be streamed as usual here
>> <https://mila.bluejeans.com/1365483656/webrtc>
>> And you can sign up to meet the speaker here
>> <https://calendar.google.com/calendar/selfsched?sstoken=UVBVTVF0X25Nd09LfGRlZmF1bHR8ZWQ5MmNlYWMxODI4OWVkNmUzNGU3OTE4ZDExMGI0YTk>
>>
>> Don't even think about it! Decide to come to the tea talk and let your
>> feet spontaneously guide the way.
>> Michael
>>
>> *TITLE* Spontaneous movements dominate cortical activity during
>> sensory-guided decision making
>>
>> *KEYWORDS *neuroscience, decision-making, neuro-imaging
>>
>> *ABSTRACT*
>> Animals continually produce a wide array of spontaneous and learned
>> movements and undergo rapid internal state transitions. Most work in
>> neuroscience ignores this “internal backdrop” and instead focuses on
>> neural activity aligned to task-imposed variables such as sensory stimuli.
>> We sought to understand the joint effects of internal backdrop vs.
>> task-imposed variables. We measured neural activity using calcium imaging
>> via a widefield macroscope during decision-making. Surprisingly, the impact
>> of the internal backdrop dwarfed task-imposed sensory and
>> cognitive signals. This dominance was comparable in novice and expert
>> decision-makers and was even stronger in single neuron measurements from
>> frontal cortex. These results highlight spontaneous and learned movements
>> as the main determinant of large-scale cortical activity. By leveraging a
>> wide array of animal movements, our model offers a very general method for
>> separating the impact of internal backdrop from task-imposed
>> neural activity.
>>
>> *BIO* Anne K. Churchland received her Ph.D. in neuroscience from the
>> University of California, San Francisco, advised by Dr. Stephen Lisberger.
>> She then did a postdoctoral fellowship with Dr. Michael Shadlen at the
>> University of Washington in the Physiology and Biophysics Department. Her
>> postdoctoral work focused on mechanisms of decision making in nonhuman
>> primates and included both experimental and theoretical work. The latter
>> was funded by a Pathways to Independence (K99) Award from the National Eye
>> Institute. In 2010, she became an assistant professor at Cold Spring Harbor
>> Laboratory. In starting her own laboratory, Professor Churchland began
>> studying decision making using rodent models to take advantage of emerging
>> tools for circuit dissection which are readily available in rodents. Since
>> then, her laboratory has been a major player in bringing behavioral
>> paradigms to rodents that have been successful in elucidating neural
>> mechanisms in primates. These include perceptual decision making and
>> multisensory integration. Most recently, she has teamed up with other 20
>> other researchers to for the International Brain Laboratory, a
>> collaboration between theorists and experimentalists aiming to understand
>> the neural computations supporting decision-making. Since joining Cold
>> Spring Harbor Laboratory, Professor Churchland has been the recipient of
>> awards from the McKnight Foundation, the Pew Charitable Trusts, the
>> Klingenstein-Simons Foundation, the Simons Collaboration on the Global
>> Brain, the John Merck Fund and the Chapman Foundations. In addition to her
>> scientific work, Professor Churchland runs science outreach activities at
>> public schools and co-directed the Undergraduate Research Program at Cold
>> Spring Harbor Laboratory. She also maintains a blog about neuroscience
>> research that is directed at a mainstream audience; its recent focus is on
>> reviewing papers on the preprint server. Professor Churchland also funded
>> anneslist.net, a resource highlighting women in systems and
>> computational neuroscience. She received the 2017 Louise Hanson Marshall
>> Special Recognition Award from the Society for Neuroscience for promoting
>> diversity in the field and the 2012 Janett Rosenberg Trubatch Career
>> Development Award for creativity in research prior to tenure.
>>
>> --
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>
>
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